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产品详情
产品名称
TPPP rabbit pAb
产品货号
YM-A23767
规格
50μL;100μL
种属反应
Human,Mouse,Rat
实验应用
WB
分子量
宿主
Rabbit
同种型
IgG
修饰
Unmodified
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克降性
Polyclonal
克隆号
免疫原
Synthesized peptide derived from human TPPP
特异性
This antibody detects endogenous levels of TPPP at Human, Mouse,Rat
基因名称
TPPP TPPP1
蛋白名称
TPPP
别名
Tubulin polymerization-promoting protein;TPPP;25 kDa brain-specific protein;TPPP/p25;p24;p25-alpha;
基因ID-1
11076
SwissProt
O94811
背景
细胞定位
Golgi outpost . Cytoplasm, cytoskeleton, microtubule organizing center . Cytoplasm, cytoskeleton . Nucleus . Cytoplasm, cytoskeleton, spindle . Specifically localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity). Mainly localizes to the cytoskeleton (PubMed:18028908). Also found in the nucleus; however, nuclear localization is unclear and requires additional evidences (PubMed:18028908). Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies (PubMed:15590652, PubMed:17027006). During mitosis, colocalizes with LIMK2 at the mitotic spindle (PubMed:22328514). .
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