JNK2 Rabbit mAb

产品详情

产品名称

JNK2 Rabbit mAb

产品货号

YM-A25206

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,IP,ELISA

分子量

46,54kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

推荐稀释比

IHC 1:2000-1:10000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

克隆号

PT0852R

免疫原

特异性

Endogenous

基因名称

MAPK9

蛋白名称

Mitogen-activated protein kinase 9

别名

MAPK9;JNK2;PRKM9;SAPK1A;Mitogen-activated protein kinase 9;MAP kinase 9;MAPK 9;JNK-55;Stress-activated protein kinase 1a;SAPK1a;Stress-activated protein kinase JNK2;c-Jun N-terminal kinase 2

基因ID-1

5601

SwissProt

P45984

背景

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternative

细胞定位

Cytoplasm . Nucleus . Colocalizes with POU5F1 in the nucleus. .