Glutamate Receptor 1 Rabbit mAb

产品详情

产品名称

Glutamate Receptor 1 Rabbit mAb

产品货号

YM-A25215

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,IP,ELISA

分子量

101kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

推荐稀释比

IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

克隆号

PT0846R

免疫原

特异性

Endogenous

基因名称

GRIA1

蛋白名称

Glutamate receptor 1

别名

GRIA1;GLUH1;GLUR1;Glutamate receptor 1;GluR-1;AMPA-selective glutamate receptor 1;GluR-A;GluR-K1;Glutamate receptor ionotropic;AMPA 1;GluA1

基因ID-1

2890

SwissProt

P42261

背景

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic density membrane ; Multi-pass membrane protein . Cell projection, dendrite . Cell projection, dendritic spine . Early endosome membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein . Cell junction, synapse, presynapse . Cell junction, synapse . Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression. Colocalizes with PDLIM4 in early endosomes. Displays a somatodendritic localization and is excluded from axons in neurons (By similarity). Localized to cone photoreceptor pedicles (By similarity). .