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产品详情
产品名称
HNF-4α Rabbit mAb
产品货号
YM-A25251
规格
50μL;100μL
种属反应
Human,Mouse,Rat
实验应用
WB,IHC,IF,IP,ELISA
分子量
53kD
宿主
Rabbit
同种型
IgG,Kappa
修饰
推荐稀释比
IHC 1:1000-1:5000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
克降性
克隆号
PT0708R
免疫原
特异性
Endogenous
基因名称
HNF4A
蛋白名称
Hepatocyte nuclear factor 4-alpha
别名
HNF4A;HNF4;NR2A1;TCF14;Hepatocyte nuclear factor 4-alpha;HNF-4-alpha;Nuclear receptor subfamily 2 group A member 1;Transcription factor 14;TCF-14;Transcription factor HNF-4
基因ID-1
3172
SwissProt
P41235
背景
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012],
细胞定位
Nucleus.
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