PP1α/β Rabbit mAb

产品详情

产品名称

PP1α/β Rabbit mAb

产品货号

YM-A25263

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,IP,ELISA

分子量

38kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

推荐稀释比

IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

克隆号

PT0691R

免疫原

特异性

Endogenous

基因名称

PPP1CA;PPP1CB

蛋白名称

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;Serine/threonine-protein phosphatase PP1-beta catalytic subunit;

别名

PPP1CA;PPP1A;Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;PP-1A;PPP1CB;Serine/threonine-protein phosphatase PP1-beta catalytic subunit;PP-1B;PPP1CD;

基因ID-1

5500;5499

SwissProt

P62136;P62140

背景

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, Nucleus