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产品详情
产品名称
GPER1 Rabbit mAb
产品货号
YM-A25273
规格
50μL;100μL
种属反应
Human,Mouse,Rat
实验应用
WB,IHC,IF,IP,ELISA
分子量
55kD
宿主
Rabbit
同种型
IgG,Kappa
修饰
推荐稀释比
IHC 1:1000-1:5000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
克降性
克隆号
PT0701R
免疫原
特异性
Endogenous
基因名称
GPER1
蛋白名称
G-protein coupled estrogen receptor 1
别名
基因ID-1
2852
SwissProt
Q99527
背景
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Membrane
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