IκB-α Rabbit mAb

产品详情

产品名称

IκB-α Rabbit mAb

产品货号

YM-A25274

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,IP,ELISA

分子量

36kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

推荐稀释比

IHC 1:200-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

克隆号

PT0702R

免疫原

特异性

Endogenous

基因名称

NFKBIA IKBA MAD3 NFKBI

蛋白名称

NF-kappa-B inhibitor alpha

别名

NF-kappa-B inhibitor alpha;I-kappa-B-alpha;IkB-alpha;IkappaBalpha;Major histocompatibility complex enhancer-binding protein MAD3;

基因ID-1

4792

SwissProt

P25963

背景

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011],

细胞定位

Cytoplasm, Nucleus