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产品详情
产品名称
RUNX1 Rabbit mAb
产品货号
YM-A25278
规格
50μL;100μL
种属反应
Human,Mouse,Rat
实验应用
WB,IHC,IF,IP,ELISA
分子量
43-55kD
宿主
Rabbit
同种型
IgG,Kappa
修饰
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
克降性
克隆号
PT0706R
免疫原
特异性
Endogenous
基因名称
RUNX1
蛋白名称
Runt-related transcription factor 1
别名
RUNX1;AML1;CBFA2;Runt-related transcription factor 1;Acute myeloid leukemia 1 protein;Core-binding factor subunit alpha-2;CBF-alpha-2;Oncogene AML-1;Polyomavirus enhancer-binding protein 2 alpha B subunit;PEA2-alpha B;PEBP2-alpha
基因ID-1
861
SwissProt
Q01196
背景
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus
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