CD89 Rabbit mAb

产品详情

产品名称

CD89 Rabbit mAb

产品货号

YM-A25294

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,ICC,Flow Cyt,IP

分子量

32kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

推荐稀释比

WB 1:1000-5000;IHC 1:100-300;ICC/IF 1:100-300;FC 1:100-300;IP 1:50-100

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

克隆号

PT0770R

免疫原

特异性

Endogenous

基因名称

FCAR;CD89

蛋白名称

Immunoglobulin alpha Fc receptor;IgA Fc receptor;CD antigen CD89;

别名

FCAR;CD89;Immunoglobulin alpha Fc receptor ;IgA Fc receptor;CD antigen CD89;

基因ID-1

2204

SwissProt

P24071

背景

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

细胞定位

[Isoform A.1]: Cell membrane; Single-pass type I membrane protein.; [Isoform A.2]: Cell membrane; Single-pass type I membrane protein.; [Isoform A.3]: Cell membrane; Single-pass type I membrane protein.; [Isoform B]: Secreted.; [Isoform B-delta-S2]: Secreted.