SRP72 Rabbit mAb

产品详情

产品名称

SRP72 Rabbit mAb

产品货号

YM-A25335

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,ICC,Flow Cyt

分子量

74kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

推荐稀释比

WB 1:1000-5000;IHC 1:100-300;ICC/IF 1:100-300;FC 1:100-300

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

克隆号

PT0811R

免疫原

特异性

Endogenous

基因名称

SRP72

蛋白名称

Signal recognition particle subunit SRP72;SRP72;Signal recognition particle 72 kDa protein;

别名

SRP72;Signal recognition particle subunit SRP72 ;SRP72;Signal recognition particle 72 kDa protein;

基因ID-1

6731

SwissProt

O76094

背景

This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

细胞定位

Cytoplasm. Endoplasmic reticulum.