HP1α Rabbit mAb

产品详情

产品名称

HP1α Rabbit mAb

产品货号

YM-A25402

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

WB,IHC,IF,IP,ELISA

分子量

22kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

推荐稀释比

IHC 1:400-1:2000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

克隆号

PT0410R

免疫原

特异性

Endogenous

基因名称

CBX5 HP1A

蛋白名称

Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)

别名

Chromobox protein homolog 5;Antigen p25;Heterochromatin protein 1 homolog alpha;HP1 alpha;

基因ID-1

23468

SwissProt

P45973

背景

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus