MTCO2 rabbit Rabbit mAb

产品详情

产品名称

MTCO2 rabbit Rabbit mAb

产品货号

YM-A25411

规格

50μL;100μL

种属反应

Human,

实验应用

WB,IHC,IF,IP,ELISA

分子量

21kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

推荐稀释比

IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

克隆号

PT0386R

免疫原

特异性

Endogenous

基因名称

MT-CO2 COII COXII MTCO2

蛋白名称

Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II)

别名

基因ID-1

4513

SwissProt

P00403

背景

cofactor:Copper A.,disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood.,disease:Defects in MT-CO2 are associated with tumor formation.,function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.,similarity:Belongs to the cytochrome c oxidase subunit 2 family.,

细胞定位

Cytoplasmic