IL-1 β Rabbit mAb

产品详情

产品名称

IL-1 β Rabbit mAb

产品货号

YM-A25440

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IF,IP,ELISA

分子量

31kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

推荐稀释比

WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

克隆号

PT0689R

免疫原

特异性

Endogenous

基因名称

IL1B IL1F2

蛋白名称

Interleukin-1 beta (IL-1 beta) (Catabolin)

别名

Interleukin-1 beta;IL-1 beta;Catabolin;

基因ID-1

3553

SwissProt

P01584

背景

interleukin 1 beta(IL1B) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008],

细胞定位

Secreted