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产品详情
产品名称
RPS6 Rabbit mAb
产品货号
YM-A25450
规格
50μL;100μL
种属反应
Human,Mouse,Rat
实验应用
WB,IHC,IF,IP,ELISA
分子量
31kD
宿主
Rabbit
同种型
IgG,Kappa
修饰
推荐稀释比
IHC 1:1000-1:5000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
克降性
克隆号
PT0676R
免疫原
特异性
Endogenous
基因名称
RPS6
蛋白名称
40S ribosomal protein S6
别名
RPS6;OK/SW-cl.2;40S ribosomal protein S6;Phosphoprotein NP33
基因ID-1
6194
SwissProt
P62753
背景
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed
细胞定位
Cytoplasm,Nucleus
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