GCLC Rabbit mAb

产品详情

产品名称

GCLC Rabbit mAb

产品货号

YM-A25481

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

WB,IF,IP,ELISA

分子量

73kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

推荐稀释比

WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

克隆号

PT0611R

免疫原

特异性

Endogenous

基因名称

GCLC

蛋白名称

Glutamate--cysteine ligase catalytic subunit

别名

GCLC;GLCL;GLCLC;Glutamate--cysteine ligase catalytic subunit;GCS heavy chain;Gamma-ECS;Gamma-glutamylcysteine synthetase

基因ID-1

2729

SwissProt

P48506

背景

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010],

细胞定位

Cytoplasm