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产品详情
产品名称
PDGFR-α Rabbit mAb
产品货号
YM-A25488
规格
50μL;100μL
种属反应
Human,Mouse,Rat,
实验应用
WB,IF,IP,ELISA
分子量
190kD
宿主
Rabbit
同种型
IgG,Kappa
修饰
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
克降性
克隆号
PT0591R
免疫原
特异性
Endogenous
基因名称
PDGFRA PDGFR2 RHEPDGFRA
蛋白名称
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
别名
Platelet-derived growth factor receptor alpha;PDGF-R-alpha;PDGFR-alpha;Alpha platelet-derived growth factor receptor;Alpha-type platelet-derived growth factor receptor;CD140 antigen-like family member A;CD140a antigen;Platelet-derived growth factor alpha receptor;Platelet-derived growth factor receptor 2;PDGFR-2;CD antigen CD140a;
基因ID-1
5156
SwissProt
P16234
背景
platelet derived growth factor receptor alpha(PDGFRA) Homo sapiens This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell projection, cilium . Golgi apparatus .
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