HDAC4 Rabbit mAb

产品详情

产品名称

HDAC4 Rabbit mAb

产品货号

YM-A25492

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

WB,IHC,IF,IP,ELISA

分子量

140kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

推荐稀释比

IHC 1:50-1:200;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

克隆号

PT0600R

免疫原

特异性

Endogenous

基因名称

HDAC4

蛋白名称

Histone deacetylase 4

别名

HDAC4;KIAA0288;Histone deacetylase 4;HD4

基因ID-1

9759

SwissProt

P56524

背景

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, Nucleus