Synapsin I Rabbit mAb

产品详情

产品名称

Synapsin I Rabbit mAb

产品货号

YM-A25494

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

WB,IHC,IF,IP,ELISA

分子量

74,70kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

推荐稀释比

IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

克隆号

PT0602R

免疫原

特异性

Endogenous

基因名称

SYN1

蛋白名称

Synapsin-1

别名

SYN1;Synapsin-1;Brain protein 4.1;Synapsin I

基因ID-1

6853

SwissProt

P17600

背景

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

细胞定位

Synapse